As nerves pass through the body, they enter and exit through planes of muscle that can develop scar tissue or fascial adhesions. Nerve hydrodissection, aka perineural injection therapy, or Neural Prolotherapy, aims to open the constricted tissue around the nerve and allow the nerve freedom to move and thereby reduce nerve related pain.
A lesser known cause of pain can come from nerve entrapment. Hydrodissection can provide almost immediate relief for some patients. It's a great adjunct therapy to prolotherapy to help address any co-existing conditions. As nerve hydrodissection treatment doesn't involve surgery, there's no downtime. In fact, some patients who have already had surgery and are still in pain may benefit from this therapy. Dr. Sorr will work closely with you to decide on the number of sessions needed to alleviate the underlying issues.
D5W (5% Dextrose Water) is the most common solution injected since it is safe and nontoxic. Dextrose, another name for glucose or sugar, has been shown to exert pain-relieving benefits by binding to the TrpV1 receptor in the pain signalling pathway thereby decreasing pain. Hydrodissection effectively separates redundant fibers of fascia that constricts nerve paths without surgery. Other benefits can include relief from:
Benefits can be seen anywhere from 1-3 treatments.
No, the concentration of sugar is very low and will not spike blood sugar levels. Since sugar is non-toxic and not a drug, there are no side effects other than swelling or bruising.
It is unlikely to damage a nerve using ultrasound guided injections since the nerve is visualized on screen in real time. Nerves are protected by a sheath that is more difficult to penetrate using the dilute sugar water solution.
Growth factors are small proteins signals that your body secretes to give cells in that area the message to begin healing. All cells in our body respond to signals and when instructed to do so, carry out the message. Examples of growth factors are TGF-B3, VEGF, EGF, and PDGF which stimulate collagen, blood vessel, and cellular growth to occur.
Platelets are a common source of growth factors from your own body. Via a blood draw just before your treatment, we separate the platelets from the red blood cells and excess plasma to create a concentrated solution called PRP or platelet rich plasma. Other growth factors may be used from acellular sterile growth factors isolated from bone marrow or placental MSC (medicinal signaling cells aka mesenchymal stem cells).